Cell Biology and Physiology Research Faculty

BSGP Research Faculty and Interest Areas


Biochemistry and Molecular BiologyBiochemistry Photo

Natalie L. Adolphi, PhD
Use of magnetic nanoparticles for disease detection and therapy, and nanoparticle physical properties, such as size and surface charge, affect the interaction of nanoparticles with cells and organisms.

William Anderson, PhD
Bioconjugate chemistry, biosensors, membrane bound enzyme arrays, biomedical education.

Marco Bisoffi, PhD
Mechanisms of cancer metastasis, androgen independence in prostate cancer, telomere biology.

Cristian Bologa, PhD
Preclinical drug discovery, with focus on cheminformatics and screening informatics.

William Sherman Garver, PhD
Genetics, nutrition and metabolism involved in maintaining energy balance.

Robert H. Glew, PhD (retired)
Maternal/child health problems in sub-Saharan Africa, fatty acid metabolism, sickle cell anemia.

Jeffrey K. Griffith, PhD
Telomere biology, genetic polymorphisms and chromosome structure in cancer.

Chien-An Andy Hu, PhD
Programmed celld eath (apoptosis and autophagy) in cancer and human genetic disease, molecular enzymology of proline metabolism.

Tudor Oprea, MD/PhD
Drug discovery, cheminformatics, molecular modeling, virtual screening.

Robert A. Orlando, PhD
Obesity and cardiovascular disease, LDL receptor family, proteoglycans, Alzheimer's disease.

Marcy P. Osgood, PhD
Biochemical education strategies, peer-assisted/cooperative learning techniques.

Karlett J. Parra, Ph.D.
Metabolic/nutritional control of proton transport/cellular pH by V-type ATPase pumps, V-ATPase molecular motors structure/function/regulation.

Laurel Sillerud, PhD
Prostate cancer, metabolic regulation in tumors, biomedical NMR, cancer metastasis.

Yohannes Tesfaigzi, PhD (LRRI)
Mechanisms underlying the proper regulation of cell numbers in airway epithelia following inflammatory injury and their relation to chronic diseases and cancers of the lung.

Kristina Trujillo, PhD
Exploiting the wound healing properties of tumor and tumor adjacent tissue for the treatment, detection and prevention of breast cancer.

David L. Vanderjagt, PhD (retired and not taking graduate students)
Structure-based drug design, molecular modeling, cancer research, diabetes research.

Dorothy Vanderjagt, PhD (retired and not taking graduate students)
Maternal/child health in sub-Saharan Africa, nutrition assessment, sickle cell anemia, body composition.

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Cell Biology and PhysiologyCell Biology Photo

David Bear, PhD
Regulation of mRNA biosynthesis and transport in muscular dystrophies and muscle cell cancers; novel electron microscopy techniques to study gene expression.

Oscar Bizzozero, PhD
Molecular mechanisms of tissue injury in multiple sclerosis and other demyelinating disorders

Laura Gonzalez Bosc, PhD
Transcriptional regulation of vascular smooth muscle phenotype.

Rebecca Hartley, PhD
Post-transcriptional regulation of the cell cycle in cancer and embryogenesis.

Helen Hathaway, PhD
Mammary gland development and breast cancer.

Nikki Jernigan, PhD
Physiology and pathophysiology of the pulmonary vasculature.

Nancy Kanagy, PhD
Study of the mechanisms leading to altered vascular smooth muscle and endothelial cell physiology in animal models of hypertension and sleep apnea.

Paul McGuire, PhD
The role of extracellular proteinases and growth factors in the regulation of ocular angiogenesis and vascular permeability.

Eric Prossnitz, PhD
The Prossnitz lab focuses on cellular signaling mechanisms initiated by G protein-coupled receptors.

Tom Resta, PhD
Mechanisms of chronic hypoxia-induced pulmonary hypertension.

Sherry Rogers, PhD (retired)
How extracellular cues influence cell differentiation during early embryonic development.

Ben Walker, PhD
Our laboratory studies the physiology of the cardiovascular system. Of special interest are the effects of impaired oxygenation (hypoxia) on vascular regulation both in the systemic and pulmonary circulations.

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Internal MedicineInternal Medicine Photo

Ravi Durvasula, MD
Development of paratransgenic strategies for control of a variety of infectious diseases.

Douglas Jay (DJ) Perkins, PhD
Various molecular aspects of the human host-immune response to parasites and viruses.

Marianne Berwick, PhD, MPH
Etiology and prevention of melanoma skin cancer.

Sam Lee, PhD
Molecular pathogenesis of invasive candidiasis and also investigates translational aspects of Candida infection, including mechanisms of echinocandin resistance and molecular epidemiology of oral candidiasis in immunosuppressed patients.

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Molecular Genetics and MicrobiologyMolecular Genetics Photo

Ellen Beswick, Ph.D
T cell immunology in the GI tract: Treg and Th17 differentiation and responses in antimicrobial defense, inflammation and carcinogenesis.

Judy Cannon, PhD
T cell migration, T cell signaling, immunological synapse, chemokines, selectins, intravital microscopy.

Bryce Chackerian, PhD
Interactions between virus particles and the immune system.

Vojo Deretic, PhD
Our latest interest is the process of Autophagy, an exciting new cell homeostatic process that maintains the cellular interior (organelles and cytosolic components) in a functional state, but sometimes can go awry and cause cell death.

Jeremy Edwards, PhD
Spatial temporal modeling, epidermal growth factor receptor, functional genomics technologies, sequencing.

Adriana Kajon, PhD (LRRI)
Molecular biology and evolution of respiratory adenoviruses.

Carolyn Mold, PhD
Acute phase proteins particularly C-reactive protein in the regulation of inflammation and autoimmunity through interactions with Fc receptors and induction of cytokines.

Scott Ness, PhD
Stem cells, oncogenes, signaling and the regulation of transcription, differentiation and cell cycle.

Mary Ann Osley, PhD
Histone modifications and the regulation of gene expression and DNA damage repair.

Michelle Ozbun, PhD
Human papillomaviruses, animal papillomaviruses, cervical cancer, skin cancer, epithelial biology, cancer biology, virology.

David Peabody, PhD
RNA-protein interactions, translational regulation, virus assembly.

Robert L. Rubin, PhD
The main focus of the laboratory is on systemic autoimmunity and how environmental factors such as drugs and toxicants influence development of autoreactive T cells.

Xuexian Yang, PhD
T helper cell, TH17, inflammatory and autoimmune disease, neuroinflammation, allergy, transcriptional control, cytokine signaling.

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NeurosciencesNeurosciences

Andrea Allan, PhD
Neurochemical mechanisms of learning, memory, and substance abuse.

Jonathan Brigman, PhD
Biological basis of maladaptive behavioral changes in addiction.

Kevin Caldwell, PhD
SSignal transduction in learning, memory, and cognitive dysfunctions.

John Connor, PhD
Ca2+ and related second control of normal and degenerative responses in brain neurons.

Lee Anna Cunningham, PhD
Neuron death, protection, and repair in animal models of Parkinson's Disease and stroke.

Erin Milligan, PhD
Glial involvement, neuroimmune interactions, and gene therapy in chronic pain.

L. Donald Partridge, PhD
Electrophysiology and calcium imaging of synaptic plasticity.

Nora Perrone-Bizzozero, PhD
Posttranslational regulation of neuronal genes in development and regeneration.

Linda Saland, PhD (retired)
Functional mechanisms of opioid receptors in animal models of chronic pain and alcoholism.

Daniel Savage, PhD
Long-term neuronal consequences of maternal ethanol consumption.

C. William Shuttleworth, PhD
Basic mechanisms of cell death in stroke and spreading depression.

C. Fernando Valenzuela, MD/PhD
Neurophysiological consequences of alcohol exposure during development.

James Wallace, PhD
Developmental regulation of neurotransmitter phenotypes.

Michael Wilson, PhD
Molecular genetics of synaptic transmission in brain development and disease.

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PathologyPathology

Elaine Bearer, MD/PhD
Herpes simplex virus hijacks APP, associated with Alzheimer's disease, for transport. Platelet shape change requires activity of Arp2/3 complex.

Tione Buranda, PhD
Cellular biophysics and membrane structure.

Jennifer M. Gillette, PhD
Stem cell and tumor cell signaling within the bone marrow microenvironment. Quantitative fluorescence microscopy and super resolution imaging.

Brian Hjelle, MD
Pathogenesis, immunology, epidemiology, molecular biology and diagnosis of human virus infections.

Richard Larson, MD/PhD
Cell adhesion and ligand design in the application to disease diagnosis, biosensor design and imaging agent development.

Diane Lidke, PhD
Biophysical and live cell imaging approaches to study protein dynamics and interactions during signal transduction.

Janet Oliver, PhD
IgE receptors of mast cells and basophils; spatio-temporal modeling of signal transduction in allergy and leukemogenesis.

Angela Wandinger-Ness, PhD
Stem cells, kidney cell biology and mechanisms of protein trafficking.

Julie Wilder, PhD (LRRI)
Genetic regulation of inflammatory responses to allergens and infections agents, and understanding the development and consequences of immune responses in the lungs.

Thomas Williams, MD
Genetics of the MHC in human and non-human primates.

Cheryl Willman, MD
Genomics and genetics of acute leukemia; genomics for molecular classification, risk assessment, and target. identification

Bridget Wilson, PhD
Membrane microdomains, calcium signaling and modeling, signal transduction.

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Toxicology and PharmacologyToxicology

Edward G. Barrett, PhD (LRRI)
Fetal and infant immune maturation.

Scott Burchiel, PhD
Immunotoxicity and carcinogenicity of environmental agents.

Matthew Campen, PhD
How the cardiovascular system may become impaired as a result of insults to the respiratory system.

Yung-Sung Cheng, PhD (LRRI)
Aerosol drug delivery; the design and test of air sampling instruments; deposition in the respiratory tract; air quality of ambient, occupational and indoor environments; measurement of radon and radon progeny; inhalation toxicology.

Linda Felton, PhD
Drug delivery systems and pharmaceutics.

Changjian Feng, PhD
Structure/function and reaction mechanism of nitric oxide synthase.

Donald Godwin, PhD
Development and testing of novel sunscreen formulations to prevent skin cancer.

Pamela Hall, PhD
Immune system defense against invasive infection by S. aureus, particularly by CA-MRSA.

Laurie Hudson, PhD
Signal transduction pathways regulating functional and phenotypic plasticity in normal tissue and tumor metastasis.

Jim Liu, PhD
Free radical and oxidative stress in disease development, including carcinogenesis and brain injury.

Yubin Miao, PhD
Novel radiolabeled peptides for cancer diagnosis and therapy using radiolabeled alpha-melanocyte stimulating hormone (a-MSH) peptides for melanoma detection and therapy.

Joe L. Mauderly, DVM (LRRI)
Health effects of air pollution.

Jacob McDonald, PhD(LRRI)
Implementation of analytical chemistry and aerosol science to address questions of environmental relevance

Matthew Reed, PhD/DABT (LRRI)
Toxicology of inhaled toxicants and chemical and biochemical toxicology.

JeanClare Seagrave, PhD (LRRI)
Mechanisms of health effects of inhaled materials including air pollution and cigarette smoke.

Bobby Scott, PhD (LRRI)
Mechanisms-based modeling of low-dose radiation and chemical-induced stochastic effects(mutations, apoptosis, neoplastic transformation).

Mohan Sopori, PhD (LRRI)
The immunosuppresive and anti-inflammatory properties of nicotine are mediated through its direct interaction with immune cells and indirectly through the sympathetic autonomic nervous system.

Todd A. Thompson, PhD
Investigate the molecular pathways in breast and prostate cancer development, prevention, and treatment.

Graham Timmins, PhD
Investigate the role of UV-induced radicals in melanoma; drug radicals in antibiotic action.

Mary K. Walker, PhD
Study the molecular mechanisms of the Ah receptor in cardiovascular physiology and disease.

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